Progenitor cell trafficking in the vascular wall
نویسندگان
چکیده
منابع مشابه
Vascular wall progenitor cells in health and disease.
The vasculature plays an indispensible role in organ development and maintenance of tissue homeostasis, such that disturbances to it impact greatly on developmental and postnatal health. Although cell turnover in healthy blood vessels is low, it increases considerably under pathological conditions. The principle sources for this phenomenon have long been considered to be the recruitment of cell...
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A rapidly increasing body of data suggests an essential role of endothelial progenitor cells (EPCs) in vascular regeneration, formation of new vessels in cardiovascular diseases and also in tumor vasculogenesis. Moreover, recent data obtained from clinical studies with anti-angiogenic drugs in tumor therapy or with pro-angiogenic stimuli in ischemic disorders implicate a predictive role of the ...
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Here, we report the existence of endothelial precursor (EPC) and stem cells in a distinct zone of the vascular wall that are capable to differentiate into mature endothelial cells, hematopoietic and local immune cells, such as macrophages. This zone has been identified to be localized between smooth muscle and adventitial layer of human adult vascular wall. It predominantly contains CD34-positi...
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Blood vessel formation plays an essential role in many physiologic and pathologic processes, including normal tissue growth and healing, as well as tumor progression. Endothelial progenitor cells (EPC) are a subtype of stem cells with high proliferative potential that are capable of differentiating into mature endothelial cells, thus contributing to neovascularization in tumors. In response to ...
متن کاملMast Cell Progenitor Trafficking in Allergic Airway Inflammation
Dahlin, J. 2013. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation. Acta Universitatis Upsaliensis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 932. 41 pp. Uppsala. ISBN 978-91-554-8741-6. Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that conta...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2009
ISSN: 1538-7933,1538-7836
DOI: 10.1111/j.1538-7836.2009.03406.x